A natural polyphenolic compound that has been established to have the therapeutic effect for the management of inflammation associated with cardiovascular disease, diabetes, metabolic syndrome, neuroinflammation and osteoarthritis by attenuating the activation of immune cells and release of pro-inflammatory mediators through the inhibition of the transcriptional factors and inhibition of microglia and activate the activities of sirtuins including sirtuin-1.

A Phyto polyphenol compound that has many biological properties such as anti-inflammatory, antioxidant, antiproliferative and anticarcinogenic. Apigenin can cross the blood-brain barrier, which serves as an effective anti-inflammatory ingredient to reduce neuroinflammation. Apigenin promotes different anti inflammatory pathways, including p38/MAPK and PI3K/Akt, and prevents the IKB degradation and nuclear translocation of the NF-ΚB and reduction of COX-2 activity. Apigenin is also served as a supporting treatment in alleviating the arthritis symptom by inhibiting the collagenase activity.

A polyphenol antioxidant with an effective anti-inflammatory property. It has been established that kaempferol has a therapeutic effect on inflammation-related diseases such as allergies, arthritis, diabetes, and neurological regression by regulating the expression of genes that are involved in inflammation and inhibit the transcription factors and protein kinases. In addition, Kaempferol is categorised as a novel therapeutic agent for treating rheumatoid arthritis as it inhibits the synovial fibroblast proliferation and production of MMPs, COX-2 and PGE2.

General

Mix 1ml (equivalent to 15 drops) per serving with lukewarm water and drink daily. Best taken on empty stomach.

Sublingual administration

Place 15 drops under the tongue, swirl for a few minutes before swallowing.

Storage recommendation

4 – 8 Celcius.

Shelf Life:

2 years after manufacturing. Mild sedimentation may occur and is considered normal within product shelf life.